Data of craniopharyngioma management, recurrence and endocrine outcomes
Ziad Hussein
Nigel Glynn
Niamh Martin
Akram Alkrekshi
Nigel Mendoza
Ramesh Nair
Katherine McCullough
Hani J. Marcus
Neil Dorward
Joan Grieve
Naomi Fersht
Pierre-Marc Bouloux
Maralyn Druce
Stephanie Baldeweg
10.5522/04/12023025.v1
https://rdr.ucl.ac.uk/articles/dataset/Data_of_craniopharyngioma_management_recurrence_and_endocrine_outcomes/12023025
<p></p><p>Craniopharyngiomas are neoplasms of the sellar and parasellar region
which develop from the epithelium of the primordial craniopharyngeal canal
(Rathke's pouch). Despite their WHO classification as type 1 tumours,
craniopharyngiomas are associated with multiple comorbidities including
hypopituitarism, obesity and somnolence</p>
<p><sup> </sup>In this clinical study, we investigated
the management and outcomes of a large cohort of patients with
craniopharyngioma, both childhood and adult-onset, from three tertiary
endocrine centres in the United Kingdom. The primary aim of this study
was to examine temporal trends in the management of craniopharyngioma and their
impact on long-term patient’s endocrine function.</p><br><p></p>
2020-03-26 16:40:56
Craniopharyngiomas
Endocrinology & Metabolism
Hypopituitarism
Health Care