Two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FHR-4 and FH levels

2020-01-29T15:09:27Z (GMT) by Valentina Cipriani Laura Lorés-Motta

The data repository consists of four files of summary statistics from the two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FH and FHR-4 levels:


METAANALYSIS_FH_ALL-adjAMD.txt (tab-separated values file; size: 448Mb)

METAANALYSIS_FH_controls.txt (tab-separated values file; size: 448Mb)

METAANALYSIS_FHR4_ALL-adjAMD.txt (tab-separated values file; size: 432Mb)

METAANALYSIS_FHR4_controls.txt (tab-separated values file; size: 432Mb)


The single-cohort GWASs were carried out using EPACTS software available at http://genome.sph.umich.edu/wiki/EPACTS; effect size estimates and standard errors of single variants seen in both cohorts were subsequently combined in a fixed-effect meta-analysis using METAL software available at http://csg.sph.umich.edu/abecasis/metal/download/.


More details are provided in the Readme.pdf file.