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Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes

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<p><br></p> <p>This directory contains the data necessary to generate the results described </p> <p>in the manuscript: 'Biomedical consequences of elevated cholesterol-containing </p> <p>lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes'.</p> <p><br></p> <p>## File content </p> <p><br></p> <p>* Figure2_annotations.tsv.gz</p> <p>    Contains cell annotations used in figure 2. The annotations are either '.' </p> <p>    when the p-value is larger than 0.05, or the point estimate</p> <p>    (log odds ratio, or mean difference).</p> <p>* Figure2_pvalues.tsv.gz</p> <p>    Contains the -log10(p-values) used to colour the cells in figure 2. </p> <p>* Figure3_edges.tsv.gz</p> <p>    Lists the network connections between the `Source` (the exposure) and</p> <p>    the `Target` (the outcome), as well as the effect direction. </p> <p>* Figure3_nodes.tsv.gz</p> <p>    Lists the node text for the network presented in Figure 3.</p> <p>* Figure4_tables.xlsx</p> <p>    Lists the point estimates with standard error and confidence intervals</p> <p>    for the forest plot presented in Figure 4. Includes a prioritization </p> <p>    column.</p> <p>* Figure5_tables.xlsx</p> <p>    Lists the point estimates with standard error and confidence intervals</p> <p>    for the forest plot presented in Figure 5. Includes a prioritization </p> <p>    column.</p> <p>* Figure6_exposure_panel.tsv.gz</p> <p>    Contains the -log10(p-values) of the Kolmogorov-Smirnov tests.</p> <p>* Figure6_outcome_panel.tsv.gz</p> <p>    Contains the -log10(p-values) of the Kolmogorov-Smirnov tests.</p> <p><br></p>

Funding

PG/18/5033837

PG/22/10989

Accelerator Award (round 1)

British Heart Foundation

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