CSF Nfl results CLN2 disease
datasetposted on 03.12.2021, 17:14 authored by Wendy HeywoodWendy Heywood, Katharina Iwan, Paul GissenPaul Gissen, Henrik ZetterbergHenrik Zetterberg, Amanda HeslegraveAmanda Heslegrave, Nina PatelNina Patel, Mina Borisova, laura lee, Rebecca Bower, Sara MoleSara Mole, Philippa MillsPhilippa Mills, Kevin MillsKevin Mills
Dataset updated with alternative patient numbering to match manuscript. Excel data set of longditudinal CSF Nfl measurments (pg/ml) for pediatric patients undergoing ERT.
The collection of samples for this study has ethical approval (13/LO/0168; IRAS ID 95005; London-Bloomsbury Research Ethics Committee) and Health Research Authority (HRA) approval and all participants provided informed written consent
CSF NfL protein concentration was measured on a Simoa HD-X analyser using the Simoa NF-light Advantage assay kit (Quanterix, Billerica, MA) after being diluted 100x.