Dataset updated with alternative patient numbering to match manuscript. Excel data set of longditudinal CSF Nfl measurments (pg/ml) for pediatric patients undergoing ERT.
The collection of samples for this study has ethical approval
(13/LO/0168; IRAS ID 95005; London-Bloomsbury Research Ethics Committee) and
Health Research Authority (HRA) approval and all participants provided informed written
consent
CSF NfL protein concentration was measured on a Simoa HD-X analyser
using the Simoa NF-light Advantage assay kit (Quanterix, Billerica, MA) after
being diluted 100x.
Funding
Biomarkers for CLN2 disease Battens Disease Research Support and Association