posted on 2025-01-28, 09:29authored byMaxime Beau, David Herzfeld, Francisco Naveros, Marie Hemelt, Federico D'Agostino, Marlies Oostland, Alvaro Sánchez-López, Young Yoon Chung, Michael Maibach, Stephen Kyranakis, Hannah N. Stabb, Gabriela Martínez Lopera, Agoston Lajko, Marie Zedler, Shogo Ohmae, Nathan Hall, Beverley ClarkBeverley Clark, Dana Cohen, Stephen Lisberger, Dimitar Kostadinov, Court Hull, Michael HausserMichael Hausser, Javier Medina
<p dir="ltr"><b>The C4 Database</b></p><p dir="ltr">This is the official repository for the <a href="https://eur01.safelinks.protection.outlook.com/?url=https://en.wikipedia.org/wiki/Hierarchical_Data_Format&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530713351|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=l7Ly/S8h6dfV88FnSvU6wTybzu9MY4ucfcV6iY2u23w=&reserved=0" target="_blank">hdf5</a> datasets of the cerebellar cell-type classification collaboration (C4), published as a companion to the paper "A deep-learning strategy to identify cell types across species from high-density extracellular recordings" published in <i>Cell</i> (<a href="https://eur01.safelinks.protection.outlook.com/?url=https://www.biorxiv.org/content/10.1101/2024.01.30.577845v2&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530724806|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=+rBsS85l6popjtNztg1DkTJxQsBT10MfjqrbWe/17DM=&reserved=0" target="_blank">https://doi.org/10.1016/j.cell.2025.01.041</a>).</p><p dir="ltr">Instructions to use the cell-type classifier, links to download these datasets, and a data explorer can be found at <a href="https://eur01.safelinks.protection.outlook.com/?url=https://www.c4-database.com/&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530736527|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=IWhE9iRGwMFcBm1mwQ5U4nprqhVvp1hJ/hL6xWJbQho=&reserved=0" target="_blank">https://www.c4-database.com</a>.</p><p dir="ltr">The specifications of the fields, data types and data formats stored in the <a href="https://eur01.safelinks.protection.outlook.com/?url=https://en.wikipedia.org/wiki/Hierarchical_Data_Format&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530747931|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=1PyWUvNMB5FkR5WqSOUmkcKMcH79Ughih8sD2hXqOpA=&reserved=0" target="_blank">hdf5</a> binary files can be found at <a href="https://eur01.safelinks.protection.outlook.com/?url=https://www.tinyurl.com/c4database&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530763399|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=KMbHm+Ln8pQOxWPqok6xMyhieSd24LIudYcPSQas4i0=&reserved=0" target="_blank">https://www.tinyurl.com/c4database</a>. <a href="https://eur01.safelinks.protection.outlook.com/?url=https://en.wikipedia.org/wiki/Hierarchical_Data_Format&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530777814|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=un5vN2R7ugo2Fv43yXXJKZep9Q2Jlyck9+gN5Pm3Qt0=&reserved=0" target="_blank">Hdf5</a> files can be easily opened with Python, MATLAB and many other programming languages.</p><p dir="ltr"><b>Using and Citing the C4 Database</b></p><p dir="ltr">The data and visualizations on this website are intended to be freely available for use by the scientific community. The C4 dataset is licensed under the <a href="https://eur01.safelinks.protection.outlook.com/?url=https://creativecommons.org/licenses/by-nc-sa/4.0/&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530790024|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=aw+HVpZBdwvetSOgQIVMmdSS9wI1sn/jKooRdoenJq4=&reserved=0" target="_blank">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License</a>, while our classifier is licensed under the <a href="https://eur01.safelinks.protection.outlook.com/?url=https://www.gnu.org/licenses/#GPL&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530801739|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=m6wYL3w/TyG6Lo7OApf60I3qnLylkySA5HqTFOt3r8w=&reserved=0" target="_blank">GNU General Public License v3.0</a> as part of <a href="https://github.com/m-beau/NeuroPyxels" target="_blank">NeuroPyxels</a>. If you download and use our data for a publication, and/or if you would like to refer to the database, please cite <a href="https://eur01.safelinks.protection.outlook.com/?url=https://doi.org/10.1016/j.cell.2025.01.041&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530813032|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=krdcn2FfHi2FiJ6XcTNvck6Oyn3kLL6pH1lWt8ckOyU=&reserved=0" target="_blank">Beau et al., 2025, <i>Cell</i></a> together with the <a href="https://github.com/m-beau/NeuroPyxels" target="_blank">NeuroPyxels repository</a> (<a href="https://eur01.safelinks.protection.outlook.com/?url=https://zenodo.org/records/5509776&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530824388|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=8tptbCLwsPMN0tnKOgpW4p6qb2itOdCkhfk87sDAo3s=&reserved=0" target="_blank">Beau et al., 2021, <i>Zenodo</i></a>), and include the link to the C4 online portal <a href="https://eur01.safelinks.protection.outlook.com/?url=https://www.c4-database.com/&data=05|02|christine.buckley@ucl.ac.uk|38143a9b01cd4bf12d3608dd5a5ed511|1faf88fea9984c5b93c9210a11d9a5c2|0|0|638766085530836005|Unknown|TWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ==|0|||&sdata=F50j21Xmm0SBZ8HyB7a1SDVmYQabsLAJzLdGOLyjubQ=&reserved=0" target="_blank">https://www.c4-database.com</a> in your methods section. Thank you!</p>