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Data and code for Figures for the article “Real-time 3D movement correction for two-photon imaging in behaving animals”

dataset
posted on 27.04.2020 by Antoine Valera, Victoria Griffiths, Angus Silver

Code and data to generate figures found in Griffiths et al, 2020 "Real-time 3D movement correction for two-photon imaging in behaving animals". Simply download all the files and add them to you matlab path. You can then run the script corresponding to the figures of interest. Scripts are named plot_figure_#.m and will load data from the subfolder with the same name. More information is available in each script. For figures that used patch or volume imaging, the data provided usually corresponds to extracted data. When computing the performance of our Real Time 3D Movement Correction (RT-3DMC), we often use a metric called UDE (Uncorrected Displacement Error), which corresponds to an independent measurement of the remaining movement after RT-3DMC, as estimated by a subpixel registration algorithm [1]. The UDE values indicate how much residual movement is present (in the absence or presence of RT-3DMC) when the animal is behaving (running/licking/swimming).

Funding

Synaptic and neuronal determinants of network function: Application of new optical and computational tools.

Wellcome Trust

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The cellular basis of information processing in a cerebellar microcircuit

Wellcome Trust

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Nonlinear synaptic integration in morphologically simple and complex neurons

European Research Council

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Development and dissemination of high speed 3D acousto-optic lens two-photon microscopy for in vivo imaging

National Institute of Neurological Disorders and Stroke

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Optimization and dissemination of non-linear Acousto-Optic Lens two-photon microscopy for high speed multiscale 3D imaging

National Institute of Neurological Disorders and Stroke

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From vision to action: Systems analysis of sensorimotor circuitry controlling visually-guided behaviour.

Wellcome Trust

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Plasticity of dendritic computations during active network states

European Commission

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Neurociência Computacional e de Sistemas ; #2018/20277-0

"All optical" 3D exploration of neuronal computations in sensory neocortical microcircuits

International Human Frontier Science Program Organization

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