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Extracellular spinal recordings: dorsal and ventral root conduction velocities

Afferent (dorsal root) and efferent (ventral root) conduction velocity datasets associated with Pocratsky et al 2023, Science Translational Medicine


Data generated from isolated spinal cord preparations with dorsal and ventral roots attached. Groups: littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko (Cdx2::FlpO;Tor1a-frt/frt) mice that develop early onset generalised torsional dystonia.


Conduction_velocity.xlsx - datafile: dorsal and ventral root conduction velocities (whole root stimulation at 2x threshold)


Conduction_time.xlsx - datafile: scaled conduction times for dorsal and ventral roots. 


Full methodological detail can be found in publication

Funding

Tuning spinal motoneurons for movement.

Wellcome Trust

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The contribution of spinal circuit dysfunction to movement disorganisation in dystonia

Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia

Medical Research Council

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