dataset
posted on 2023-09-14, 16:08 authored by Richard MottRichard Mott, William Valdar, Leah Solberg Woods, Dominique Gauguier, Sarah Burnett-Stuart, Paul Klenerman, WO Cookson, MS Taylor, Nick RawlinsNick Rawlins, Jonathan FlintJonathan Flint, huang Guan-Jhong, Shifman Sagiv, Martina JohannessonMartina Johannesson, Binnaz Yalcin, JM Taylor<p>Genotypes, phenotypes and gene expression of 2000 heterogeneous stock mice. These are previously published data (<a href="https://doi.org/10.1101/gr.088120.108" target="_blank">10.1101/gr.088120.108, </a>combined together as used in the study “Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing” (GBIO-D-23-00451)</p>
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<p>The papers are:</p>
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<p>(i) Genotypes and physiological phenotypes</p>
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<p>Valdar W, Solberg LC, Gauguier D, Burnett S, Klenerman P, Cookson WO, Taylor MS, Rawlins JN, Mott R, Flint J. Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet. 2006 Aug;38(8):879-87. doi: 10.1038/ng1840. Epub 2006 Jul 9. PMID: 16832355.</p>
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<p>(ii) Gene expression traits:</p>
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<p>Huang GJ, Shifman S, Valdar W, Johannesson M, Yalcin B, Taylor MS, Taylor JM, Mott R, Flint J. High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues. Genome Res. 2009 Jun;19(6):1133-40. doi: 10.1101/gr.088120.108. Epub 2009 Apr 17. PMID: 19376938; PMCID: PMC2694476.</p>
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Funding
Wellcome Trust
History
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