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Images used for 3D reconstruction of an entire triceps surae muscle from a SOD1G93A mouse, following intraneural engraftment of mESC-derived motor neurons

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posted on 2023-11-30, 17:39 authored by Barney BrysonBarney Bryson, Alexandra Kourgiantaki, Dai JiangDai Jiang, Andreas DemosthenousAndreas Demosthenous, Linda GreensmithLinda Greensmith

Compressed jpeg files, obtained from confocal tile-scans of serial sections through an entire triceps surae muscle, which were used to generate a 3D reconstruction of the muscle from a late-stage SODG93A mouse, to show robust projection of GFP+ axons from engrafted motor neurons throughout all regions of the muscle.

The 3D reconstruction is published as a supplementary video in our eLife publication.

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