In vivo electromyogram recordings from hindlimb muscles
dataset
posted on 2023-03-27, 14:20 authored by Amanda PocratskyAmanda Pocratsky, Filipe Do Nascimento Xavier FernandesFilipe Do Nascimento Xavier Fernandes, Gorkem OzyurtGorkem Ozyurt, Ian WhiteIan White, Roisin Sullivan, Calvin Smith, Sunaina SuranaSunaina Surana, Marco BeatoMarco Beato, Rob BrownstoneRob Brownstone<p><strong>Electromyogram (EMG) recording dataset associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em></p>
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<p>Data generated from preweaned wildtype mice (C57Bl/6J) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. Muscle activity was measured from gastrocnemius and tibialis anterior during various behavioural conditions.</p>
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<p><em><strong>EMG_quantification.xlsx: </strong></em>summary of raw and analysed data</p>
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<p>Full methodological detail can be found in manuscript</p>
Funding
The contribution of spinal circuit dysfunction to movement disorganisation in dystonia
Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia
Medical Research Council
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