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Makris et al. - scRNAseq data - Podoplanin deletion in lymph node fibroblastic stroma

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posted on 2024-12-18, 10:33 authored by Sophie ActonSophie Acton, Spiros MakrisSpiros Makris

These data provide single cell transcriptomic sequences for fibroblastic stromal cells (CD45-CD31-) and immune cells (CD45+CD31+) isolated from murine skin-draining lymph nodes. We have compared Wild type C57BL/6J mice with a genetically modified PdgframGFP-CreERT2 x Pdpnflox/flox to induce deletion of the gene encoding Podoplanin conditionally from fibroblasts.

These data support the publication - https://doi.org/10.1101/2022.12.01.518753


Files included:

Raw data h5 files, 10X Genomics transcriptional sequencing


Control_CD45-CD31-,

PDPNdel_CD45-CD31-,

Control_CD45+CD31+

PDPNdel_CD45+CD31+

Funding

Cancer Research UK Careers Development Fellowship CRUK-A19763

Rosetrees Trust Foundation PGS22 100023-CD1

Cancer Research UK Senior Fellowship CRUK - RCCSCF-May22\100001

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