These data provide single cell transcriptomic sequences for fibroblastic stromal cells (CD45-CD31-) and immune cells (CD45+CD31+) isolated from murine skin-draining lymph nodes. We have compared Wild type C57BL/6J mice with a genetically modified PdgframGFP-CreERT2 x Pdpnflox/flox to induce deletion of the gene encoding Podoplanin conditionally from fibroblasts.
These data support the publication - https://doi.org/10.1101/2022.12.01.518753
Files included:
Raw data h5 files, 10X Genomics transcriptional sequencing
Control_CD45-CD31-,
PDPNdel_CD45-CD31-,
Control_CD45+CD31+
PDPNdel_CD45+CD31+
Funding
Cancer Research UK Careers Development Fellowship CRUK-A19763
Rosetrees Trust Foundation PGS22 100023-CD1
Cancer Research UK Senior Fellowship CRUK - RCCSCF-May22\100001