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Neuroprotection by remote ischaemic conditioning in the setting of acute ischaemic stroke: a preclinical two-centre study (data repository)

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posted on 2019-12-02, 16:23 authored by Marina Basalay, Marlène Wiart, Fabien Chauveau, Chloé Dumot, Christelle Leon, Camille Amaz, Radu Bolbos, Diana Cash, Eugene Kim, Laura Mechtouff, Tae-Hee Cho, Norbert Nighoghossian, Sean M. Davidson, Michel Ovize, Derek M. Yellon

The dataset includes the data obtained from the MRI and histologic (triphenil tetrazolium chloride, TTC) analyses of the brains of rats included in the study. In addition, it includes neuroscores of these animals at the and of the recovery period.

Abbreviations:

H0 - baseline

H24 - 24 hours

ADC - apparent diffusion coefficient

HH - healthy hemisphere

AAR - area at risk (of infarction)

LVu - lesion volume uncorrected (MRI)

LVc - lesion volume corrected (MRI)

Gerriets - Gerriets' correction applied

HLVu - hemispheric lesion volume uncorrected (MRI)

HLVc - hemispheric lesion volume corrected (MRI)

HSE - hemispheric space-modifying effect of oedema (MRI)

TTCu - hemispheric lesion volume uncorrected (TTC)

MRA - magnetic resonance angiography

Funding

This study was supported by the Rubin Charitable Trust, Hatter Foundation and the National Institute for Health Research Biomedical Research Centre (NIHR-BRC) (BRC233/CM/SD/101320) and performed within the framework of the RHU MARVELOUS (ANR-16-RHUS-0009) of University Claude Bernard Lyon 1 (UCBL), within the program “Investissements d'Avenir”.

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Keywords

ischaemic stroke Remote conditioning Brain Imaging International Study Neurology and Neuromuscular Diseases Neurosciences not elsewhere classified Cardiology (incl. Cardiovascular Diseases)

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