Replay of Procedural Experience is Independent of the Hippocampus

This repository contains data necessary to reproduce the figures from our publication:

https://www.biorxiv.org/content/10.1101/2024.06.05.597547v1.full.pdf

These data are available as a zipped parent directory containing subfolders with individual data files that are required to reproduce plots for each of the main figures in the publication. Data files are a mixture of .json,.pickle, .csv and .npy files.

Data here is in a pre-processed form, originally from from neural recordings (neuropixels probes), video tracking and behavioural tracking datasets. Neural recordings were acquired from the dorsal striatum of mice during both a trained behaviour and during sleep. For the behaviour, animals performed a sequential poke task which had been learned as a skilled procedural memory. In this study we characterised this activity during task practice and post task sleep and find evidence for neural replay of procedural activity in the striatum which is not dependent on the hippocampus.

For analysis scripts see:

https://github.com/EmmettJT/procedural_replay_paper_2024