.CZI
J7520 DRG at 10nm.czi (5.19 GB)
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J7523 DRG at 10nm.tif (1.44 GB)
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J7525 DRG at 10nm.tif (885.95 MB)
DATASET
SEM_DRG_metaData.xlsx (12.03 kB)
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Scanning electron micrographs: dorsal root ganglia
dataset
posted on 2023-03-27, 13:51 authored by Amanda PocratskyAmanda Pocratsky, Filipe Do Nascimento Xavier FernandesFilipe Do Nascimento Xavier Fernandes, Gorkem OzyurtGorkem Ozyurt, Ian WhiteIan White, Roisin Sullivan, Benjamin O'CallaghanBenjamin O'Callaghan, Calvin Smith, Sunaina SuranaSunaina Surana, Marco BeatoMarco Beato, Rob BrownstoneRob BrownstoneScanning electron micrographs of dorsal root ganglia neurons associated with Pocratsky et al 2023, Science Translational Medicine
SEM_DRG_metaData.xlsx: summary of raw images provided, included code for genotypes
Images were generated from postnatal day 18 littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia.
Images were generated using the sense backscatter detector on a Gemini 300 SEM (Zeiss) and images at 10 nm resolution.
Full methodological details are provided with publication
Funding
The contribution of spinal circuit dysfunction to movement disorganisation in dystonia
Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia
Medical Research Council
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