Scanning electron micrographs: lumbar spinal cords
dataset
posted on 2023-03-27, 13:53 authored by Amanda PocratskyAmanda Pocratsky, Filipe Do Nascimento Xavier FernandesFilipe Do Nascimento Xavier Fernandes, Gorkem OzyurtGorkem Ozyurt, Ian WhiteIan White, Roisin Sullivan, Benjamin O'CallaghanBenjamin O'Callaghan, Calvin Smith, Sunaina SuranaSunaina Surana, Marco BeatoMarco Beato, Rob BrownstoneRob Brownstone<p><strong>Large area ultrastructural micographs via backscatter scanning electron microscopy associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em></p>
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<p>Data generated from postnatal day 18 littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia</p>
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<p>Images were collected using the sense backscatter detector on a Gemini 300 SEM (Zeiss) </p>
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<p><strong>SEM_SpinalCord_metaData.xlsx: </strong>summary spreadsheet of images provided, including codes for genotypes</p>
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<p>Full methodological details provided in manuscript</p>
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Funding
The contribution of spinal circuit dysfunction to movement disorganisation in dystonia
Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia
Medical Research Council
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