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Transmission electron micrographs: dorsal root ganglia

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posted on 2023-03-27, 14:27 authored by Amanda PocratskyAmanda Pocratsky, Filipe Do Nascimento Xavier FernandesFilipe Do Nascimento Xavier Fernandes, Gorkem OzyurtGorkem Ozyurt, Ian WhiteIan White, Roisin Sullivan, Benjamin O'CallaghanBenjamin O'Callaghan, Calvin Smith, Sunaina SuranaSunaina Surana, Marco BeatoMarco Beato, Rob BrownstoneRob Brownstone

Transmission electron micrographs of dorsal root ganglia neurons associated with  Pocratsky et al 2023, Science Translational Medicine 


TEM_DRG_metaData.xlsx: summary spreadsheet of raw images provided including codes for genotypes


Images were generated from postnatal day 18 littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia.


Images were generated using ThermoFisher Tecnai G2 Spirit electron microscope.


Full methodological details are provided with publication

Funding

Tuning spinal motoneurons for movement.

Wellcome Trust

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The contribution of spinal circuit dysfunction to movement disorganisation in dystonia

Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia

Medical Research Council

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    electron micrograph imagesDorsal root gangliaAnatomyNeurosciencemovement disorderdystoniaDYT1spinal cord

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