Transmission electron micrographs: dorsal root ganglia
dataset
posted on 2023-03-27, 14:27 authored by Amanda PocratskyAmanda Pocratsky, Filipe Do Nascimento Xavier FernandesFilipe Do Nascimento Xavier Fernandes, Gorkem OzyurtGorkem Ozyurt, Ian WhiteIan White, Roisin Sullivan, Benjamin O'CallaghanBenjamin O'Callaghan, Calvin Smith, Sunaina SuranaSunaina Surana, Marco BeatoMarco Beato, Rob BrownstoneRob BrownstoneTransmission electron micrographs of dorsal root ganglia neurons associated with Pocratsky et al 2023, Science Translational Medicine
TEM_DRG_metaData.xlsx: summary spreadsheet of raw images provided including codes for genotypes
Images were generated from postnatal day 18 littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia.
Images were generated using ThermoFisher Tecnai G2 Spirit electron microscope.
Full methodological details are provided with publication
Funding
The contribution of spinal circuit dysfunction to movement disorganisation in dystonia
Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia
Medical Research Council
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