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Transmission electron micrographs: globus pallidus

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Transmission electron micrographs of globus pallidus neurons associated with Pocratsky et al 2023, Science Translational Medicine


Images generated from postnatal day 18 littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. 


Images were acquired using a transmission electron microscope (ThermoFisher Tecnai G2 Spirit) with a charge-coupled device camera (Olympus SIS Morada).


TEM_GlobusPallidus_metaData.xlsx: summary spreadsheet of raw images provided, including codes for genotypes


Full methodological detail provided in manuscript

Funding

Tuning spinal motoneurons for movement.

Wellcome Trust

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The contribution of spinal circuit dysfunction to movement disorganisation in dystonia

Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia

Medical Research Council

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