Transmission electron micrographs: striatum
dataset
posted on 2023-03-27, 14:10 authored by Amanda PocratskyAmanda Pocratsky, Filipe Do Nascimento Xavier FernandesFilipe Do Nascimento Xavier Fernandes, Gorkem OzyurtGorkem Ozyurt, Ian WhiteIan White, Roisin Sullivan, Benjamin O'CallaghanBenjamin O'Callaghan, Calvin Smith, Sunaina SuranaSunaina Surana, Marco BeatoMarco Beato, Rob BrownstoneRob Brownstone<p><strong>Transmission electron micrographs of striatal neurons associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em></p>
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<p>Images generated from postnatal day 18 littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. </p>
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<p>Images were generated using a transmission electron microscope (ThermoFisher Tecnai G2 Spirit) and a charge-coupled device camera (Olympus SIS Morada).</p>
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<p><strong>TEM_Striatum_metaData.xlsx: </strong>summary spreadsheet of raw images provided, including codes for genotypes</p>
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<p>Full methodological details provided in manuscript</p>
Funding
The contribution of spinal circuit dysfunction to movement disorganisation in dystonia
Beyond The Basal Ganglia: Spinal Circuit Dysfunction As A Final Pathway For Movement Disorganisation In Tor1a Dystonia
Medical Research Council
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