Two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FHR-4 and FH levels

<p>The data repository consists of four files of summary statistics from the two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FH and FHR-4 levels: </p><p><br></p><p><b>METAANALYSIS_FH_ALL-adjAMD.txt </b>(tab-separated values file; size:<b> </b>448Mb)</p><p><b>METAANALYSIS_FH_controls.txt </b>(tab-separated values file; size:<b> </b>448Mb)</p> <p><b>METAANALYSIS_FHR4_ALL-adjAMD.txt </b>(tab-separated values file; size:<b> </b>432Mb)<br></p> <p><b>METAANALYSIS_FHR4_controls.txt </b>(tab-separated values file; size:<b> </b>432Mb)</p><p><b><br></b></p><p>The single-cohort GWASs were carried out using EPACTS software available at <a href="http://genome.sph.umich.edu/wiki/EPACTS">http://genome.sph.umich.edu/wiki/EPACTS</a>; effect size estimates and standard errors of single variants seen in both cohorts were subsequently combined in a fixed-effect meta-analysis using METAL software available at <a href="http://csg.sph.umich.edu/abecasis/metal/download/">http://csg.sph.umich.edu/abecasis/metal/download/</a>.</p><p><br></p><p>More details are provided in the <b>Readme.pdf </b>file. </p>