Two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FHR-4 and FH levels
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
The data repository consists of four files of summary statistics from the two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FH and FHR-4 levels:
METAANALYSIS_FH_ALL-adjAMD.txt (tab-separated values file; size: 448Mb)
METAANALYSIS_FH_controls.txt (tab-separated values file; size: 448Mb)
METAANALYSIS_FHR4_ALL-adjAMD.txt (tab-separated values file; size: 432Mb)
METAANALYSIS_FHR4_controls.txt (tab-separated values file; size: 432Mb)
The single-cohort GWASs were carried out using EPACTS software available at http://genome.sph.umich.edu/wiki/EPACTS; effect size estimates and standard errors of single variants seen in both cohorts were subsequently combined in a fixed-effect meta-analysis using METAL software available at http://csg.sph.umich.edu/abecasis/metal/download/.
More details are provided in the Readme.pdf file.