Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics

# README file

This file describes the code and data in the repository "Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics" DOI: 10.5522/04/14555715.

Overview of the directories:

- **data**: includes data used to generate the figures of the manuscript. The data is divided in subcategories: bnf_data, clinical_trials, coloc, drug_target_mr, drug_target_mvmr, phewas and tissue_expression, based on the different sections of the main results.

- **scripts**: includes the python code (`.ipynb`) used to generate the figures in the main body and supplementary materials. `Fig2_Fig3B_SuppFig1-3-4-34-5-33B.ipynb` has the code to generate Figure 2, Figure 3B, Supplementary Figure 1, Supplementary Figure 3, Supplementary Figure 4, Supplementary Figure 34, Supplementary Figure 5B - Supplementary Figure33 B. `Fig3A_SuppFig5-33A.ipynb` includes the code for Figure 3A, Supplementary Figure 5A to Supplementary Figure 33A. `Fig3C_SuppFig5-33C.ipynb` includes the code for Figure 3A, Supplementary Figure 5A to Supplementary Figure 33A. `SuppFig2.ipynb` includes the code for the Supplementary Figure 2.

Please contact Maria Gordillo-Maranon for any queries: maria.maranon.16@ucl.ac.uk