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Grieves et al. (2019) The place-cell representation of volumetric space in rats. All main text and supplementary figures and videos in high-resolution, zipped or mp4 format.

High-res figures and videos published in:

Roddy M. Grieves, Selim Jedidi-Ayoub, Karyna Mishchanchuk, Anyi Liu, Sophie Renaudineau and Kate J. Jeffery (2019) The place-cell representation of volumetric space in rats

In submission to NatComms, a preprint version is also available on bioRxiv: https://doi.org/10.1101/698175

Place cells are spatially modulated neurons found in the hippocampus that underlie spatial memory and navigation: how these neurons represent 3D space is crucial for a full understanding of spatial cognition. We wirelessly recorded place cells in rats as they explored a cubic lattice climbing frame which could be aligned or tilted with respect to gravity. Place cells represented the entire volume of the mazes: their activity tended to be aligned with the maze axes, and when it was more difficult for the animals to move vertically the cells represented space less accurately and less stably. These results demonstrate that even surface-dwelling animals represent 3D space and suggests there is a fundamental relationship between environment structure, gravity, movement and spatial memory.

Fig. 1 to 8, Fig. S1 to S18 and Supplementary videos S1 to S4.

High-resolution figures and original videos are provided in zipped format (1.03 GB). Supplementary video S1 is provided in high-res in .mp4 format (414.6 MB) Supplementary video S2 is provided in high-res in .mp4 format (415.3 MB).


Wellcome trust 103896AIA