Axel Petzold

Publications

• Artificial intelligence extension of the OSCAR‐IB criteria
• ДІАГНОСТИКА ТА КЛАСИФІКАЦІЯ НЕВРИТУ ЗОРОВОГО НЕРВУ
• The 2022 Lady Estelle Wolfson lectureship on neurofilaments
• Partial Parallelism Plots
• Association of retinal neurodegeneration with the progression of cognitive decline in Parkinson’s disease
• Interpretation of composite OCT/MRI findings: a clinical review of retinotopy
• A model for interrogating the clinico‐radiological paradox in multiple sclerosis: Internuclear ophthalmoplegia
• Update on Optic Neuritis: An International View
• Retinal inter-eye difference and atrophy progression in multiple sclerosis diagnostics
• Clinical review of retinotopy
• Upregulated Retinal Neurofilament Expression in Experimental Optic Neuritis
• Blood GFAP as an emerging biomarker in brain and spinal cord disorders
• Peripherin is a biomarker of axonal damage in peripheral nervous system disease
• The Role of the Inner Nuclear Layer for Perception of Persisting Tiling Inside a Monocular Scotoma
• A novel eye-movement impairment in multiple sclerosis indicating widespread cortical damage
• Applying a genetic risk score model to enhance prediction of future Multiple Sclerosis diagnosis at first presentation with optic neuritis: a cohort study in the UK Biobank
• Applying a genetic risk score model to enhance prediction of future Multiple Sclerosis diagnosis at first presentation with optic neuritis: a cohort study in the UK Biobank
• Artificial intelligence enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke
• Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders
• Interpretation of Longitudinal Changes of the Inner Nuclear Layer in MS
• Reply: Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation
• Dynamic volume-rendered optical coherence tomography pupillometry
• Neuro-Ophthalmic Implications of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Related Infection and Vaccination
• Author Correction: Seven day pre-analytical stability of serum and plasma neurofilament light chain (Scientific Reports, (2021), 11, 1, (11034), 10.1038/s41598-021-90639-z)
• Re-evaluating diabetic papillopathy using optical coherence tomography and inner retinal sublayer analysis
• UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases
• Optic neuritis and autoimmune optic neuropathies: advances in diagnosis and treatment
• The prevalence of internuclear ophthalmoparesis in a population-based cohort of individuals with multiple sclerosis
• Associations of Alcohol Consumption and Smoking with Disease Risk and Neurodegeneration in Individuals with Multiple Sclerosis in the United Kingdom
• Application of diagnostic criteria for optic neuritis – Authors' reply
• Pattern ERGs suggest a possible retinal contribution to the visual acuity loss in acute optic neuritis
• Sub-cellular level resolution of common genetic variation in the photoreceptor layer identifies continuum between rare disease and common variation
• AlzEye: longitudinal record-level linkage of ophthalmic imaging and hospital admissions of 353 157 patients in London, UK
• Normative Data and Conversion Equation for Spectral-Domain Optical Coherence Tomography in an International Healthy Control Cohort
• The Role of Optical Coherence Tomography Criteria and Machine Learning in Multiple Sclerosis and Optic Neuritis Diagnosis
• The Association of Alcohol Consumption with Glaucoma and Related Traits: Findings from the UK Biobank
• The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts
• Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders
• Automated detection of hyperreflective foci in the outer nuclear layer of the retina
• Correction: UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases (Eye, (2022), 10.1038/s41433-022-02298-7)
• Visually Evoked Potential as Prognostic Biomarker for Neuroaxonal Damage in Multiple Sclerosis From a Multicenter Longitudinal Cohort
• Remodeling of the neuromuscular junction in myasthenia gravis increases serum neurofilament heavy chain levels
• NAION or not NAION? A literature review of pathogenesis and differential diagnosis of anterior ischaemic optic neuropathies
• Correction: NAION or not NAION? A literature review of pathogenesis and differential diagnosis of anterior ischaemic optic neuropathies
• Peripheral Neuropathy in Virologically Suppressed People Living with HIV: Evidence from the PIVOT Trial
• Exploring Vitreous Haze as a Potential Biomarker for Accelerated Glymphatic Outflow and Neurodegeneration in Multiple Sclerosis: A Cross-Sectional Study
• Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis
• Differentiating glaucoma from chiasmal compression using optical coherence tomography: the macular naso-temporal ratio
• Case for a new corticosteroid treatment trial in optic neuritis: review of updated evidence
• Mild progressive multifocal leukoencephalopathy after switching from natalizumab to ocrelizumab
• Reply to the letter by Jasmin Zvorničanin on the article Prefoveal floaters as a differential diagnosis to optic neuritis: “mouches dormantes”
• A 30s test for quantitative assessment of a relative afferent pupillary defect (RAPD): the infrared pupillary asymmetry (IPA)
• An ontological foundation for ocular phenotypes and rare eye diseases
• Abnormalities of saccades and visual fixation in multiple sclerosis
• A conscious rethink: Why is brain tissue commonly preserved in the archaeological record? Commentary on: Petrone P, Pucci P, Niola M, et al. Heat-induced brain vitrification from the Vesuvius eruption in C.E. 79. N Engl J Med 2020;382:383-4. DOI: 10.1056/NEJMc1909867
• Protein aggregate formation permits millennium-old brain preservation
• Automated Pupillometry Using a Prototype Binocular Optical Coherence Tomography System
• Longitudinal Development of Peripapillary Hyper‐Reflective Ovoid Masslike Structures Suggests a Novel Pathological Pathway in Multiple Sclerosis
• Multirater Validation of Peripapillary Hyperreflective Ovoid Mass-like Structures (PHOMS)
• Expanding the phenotype of MOG antibody-associated disease (MOGAD): half a century of epilepsy and relapsing optic neuritis
• Optical coherence tomography (OCT) in neuro-ophthalmology
• Retinal asymmetry in multiple sclerosis
• Reply to “Peripapillary Hyper‐Reflective Ovoid Masslike Structures in Astronauts”
• OCT and multiple sclerosis
• Clinical aspects of the abnormal pupillary response: Shedding light on pupillary response,De pupil belicht: Klinische aspecten van de afwijkende pupilreactie
• Trends in Optic Neuritis Incidence and Prevalence in the UK and Association with Systemic and Neurologic Disease
• Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error
• Peripapillary Hyper-reflective Ovoid Mass-like Structure (PHOMS): An Optical Coherence Tomography Marker of Axoplasmic Stasis in the Optic Nerve Head
• Impaired saccadic eye movements in multiple sclerosis are related to altered functional connectivity of the oculomotor brain network
• Three "Red Lines" for Pattern Recognition-Based Differential Diagnosis Using Optical Coherence Tomography in Clinical Practice
• Acute disseminated encephalomyelitis with seizures and myocarditis: A fatal triad
• Saccadic delay in multiple sclerosis: A quantitative description
• Ambient air pollution associations with retinal morphology in the UK Biobank
• Optical coherence tomography in multiple sclerosis: A 3-year prospective multicenter study
• Vision Loss from Atypical Optic Neuritis: Patient and Physician Perspectives
• CSF levels of glutamine synthetase and GFAP to explore astrocytic damage in seronegative NMOSD
• Objective quantification of vitreous haze on optical coherence tomography scans: no evidence for relationship between uveitis and inflammation in multiple sclerosis
• Can stability of visual fixation be a measure for disability in multiple sclerosis?
• APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies
• Myelin-oligodendrocyte glycoprotein antibody-associated disease
• Relationships between retinal layer thickness and brain volumes in the UK Biobank cohort
• Seven day pre-analytical stability of serum and plasma neurofilament light chain
• Anterior visual system imaging to investigate energy failure in multiple sclerosis
• Biomarker Panel to Differentiate Brain Injury from Brain Dysfunction in Patients with Sepsis-Associated Encephalopathy
• A case series on the value of tau and neurofilament protein levels to predict and detect delirium in cardiac surgery patients
• Comment on: Morphologic Features of Buried Optic Disc Drusen on En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography
• Comparison of Associations with Different Macular Inner Retinal Thickness Parameters in a Large Cohort: The UK Biobank
• Young Adults With Anterior Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen Study
• Optic neuritis in Asian type opticospinal multiple sclerosis (OSMS-ON) in a non-Asian population: A functional-structural paradox
• Weighting evidence in MS: Obesity and neurodegeneration
• Serum neurofilament light chain withstands delayed freezing and repeated thawing
• Investigation of associations between retinal microvascular parameters and albuminuria in UK Biobank: a cross-sectional case-control study
• Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
• Optical Coherence Tomography Angiography (OCTA) in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
• The relevance of buffer system ionic strength in immunoassay development
• The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy – A prospective, pilot observational study
• Aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in immune-mediated optic neuritis at long-term follow-up
• Neuro-Ophthalmic Literature Review
• A new approach for diagnosing internuclear ophthalmoplegia with infrared oculography
• Applying the 2017 McDonald diagnostic criteria for multiple sclerosis
• A standardized protocol for quantification of saccadic eye movements: DEMoNS
• OCTiMS Study: A 3-Year Longitudinal Assessment of RNFL Thickness Measured by Optical Coherence Tomography in Patients with Relapsing-Remitting Multiple Sclerosis
• Neurodegeneration and multiple sclerosis
• Associations with Corneal Hysteresis in a Population Cohort: Results from 96 010 UK Biobank Participants
• Diagnosing and quantifying a common deficit in multiple sclerosis: Internuclear ophthalmoplegia
• Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
• Correction: The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study (PLoS One (2019) 14:1 (e0211184) DOI: 10.1371/journal.pone.0211184)
• Associations with photoreceptor thickness measures in the UK Biobank
• Cohort profile: Design and methods in the eye and vision consortium of UK Biobank
• Prefoveal floaters as a differential diagnosis to optic neuritis: “mouches dormantes”
• Time is vision in recurrent optic neuritis
• Diagnostic accuracy of optical coherence tomography inter‐eye percentage difference for optic neuritis in multiple sclerosis
• Retinal optical coherence tomography shows optic disc changes in low intracranial pressure headaches: a case report
• Software updates of OCT segmentation algorithms influence longitudinal assessment of retinal atrophy
• The Pulfrich Phenomenon: Practical Implications of the Assessment of Cases and Effectiveness of Treatment
• Peripapillary Hyperreflective Ovoid Mass-Like Structures: Is It Optic Disc Drusen or Not?: Response
• Treatment of internuclear ophthalmoparesis in multiple sclerosis with fampridine: A randomized double-blind, placebo-controlled cross-over trial
• Annualized inner retinal layer atrophy rates show a flooring effect in longstanding MS; a limitation for longitudinal OCT studies?
• Infrared pupillary asymmetry (IPA) for detection of a relative afferent pupillary defect (RAPD)
• Quantification of Visual Fixation in Multiple Sclerosis
• Vitreous haze as a novel marker for neurodegeneration in MS possibly indicating impairment of the retinal glymphatic system
• Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: An international study
• Optimal inter-eye difference thresholds in retinal nerve fiber layer and ganglion cell layer thickness for predicting a unilateral optic nerve lesion in multiple sclerosis: an international collaborative study
• Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development
• Response to: Early regression of cervical lesions in HIV-seropositive women receiving highly active antiretroviral therapy - Reply
• Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline A Study Using Optical Coherence Tomography
• The Optic Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc Drusen Using Optical Coherence Tomography
• Is there a relationship between oculomotor fatigability and perceived fatigue in multiple sclerosis?
• Has the prevalence of uveitis in patients with multiple sclerosis been overestimated?
• Optimal Inter-Eye Difference Thresholds in Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness for Predicting a Unilateral Optic Nerve Lesion in Multiple Sclerosis: An International Collaborative Study
• Progressive Multiple Sclerosis Is Associated with Accelerated Inner and Outer Retinal Layer Atrophy
• Peripapillary hyperreflective ovoid mass-like structures in multiple sclerosis are associated with disease progression
• A motor neuron strategy to save time and energy in neurodegeneration: adaptive protein stoichiometry
• Neurofilaments as biomarkers in neurological disorders
• Retinal atrophy in relation to visual functioning and vision-related quality of life in patients with multiple sclerosis
• Treating the Eyes to Help the Brain The Association Between Visual and Cognitive Function
• Cognitive impairment in patients with multiple sclerosis is associated with atrophy of the inner retinal layers
• Identification and treatment of the visual processing asymmetry in MS patients with optic neuritis: The Pulfrich phenomenon
• The role of optical coherence tomography and infrared oculography in assessing the visual pathway and CNS in multiple sclerosis
• Progression of Anterograde Trans-Synaptic Degeneration in the Human Retina Is Modulated by Axonal Convergence and Divergence
• Patterns of retrograde axonal degeneration in the visual system
• Saccadic fatigability in the oculomotor system
• Peripapillary Ovoid Hyperreflectivity in Optic Disc Edema and Pseudopapilledema
• Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error
• Retinal Asymmetry in Multiple Sclerosis
• Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study
• Multicenter reliability of semiautomatic retinal layer segmentation using OCT
• The International Multiple Sclerosis Visual System Consortium: Advancing Visual System Research in Multiple Sclerosis
• Biomarkers in neurodegenerative diseases
• Poor visual functioning and quality of life in multiple sclerosis are associated with retinal atrophy
• Prevalence of internuclear ophthalmoplegia in multiple sclerosis: a prospective infrared oculography study
• Are saccadic eye movements related to cognitive function in multiple sclerosis?
• Diagnostic accuracy of optical coherence tomography inter-eye difference in optic neuritis
• A rare variant of INO in multiple sclerosis: posterior INO of Lutz
• Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome.
• Neuro-Ophthalmic Literature Review
• Diagnostic clues and manifesting carriers in fukutin-related protein (FKRP) limb-girdle muscular dystrophy
• Glial fibrillary acidic protein is a body fluid biomarker for glial pathology in human disease
• An early case of a natural barrier to axonal degeneration
• Fampridine improves horizontal eye movements in patients with multiple sclerosis and internuclear ophthalmoplegia: a double-blind, placebo-controlled crossover study
• Optic neuritis does not mask progression of neurodegeneration affecting the macula in multiple sclerosis: a longitudinal OCT study
• Biomarkers of disease progression
• Disorders of plasma sodium.
• Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria.
• Elevated vitreous body glial fibrillary acidic protein in retinal diseases
• Maintenance Intravenous Fluids in Acutely Ill Patients
• The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.
• Elevated CSF neurofilament proteins predict brain atrophy: A 15-year follow-up study.
• Plasma neurofilament heavy chain is not a useful biomarker in Charcot-Marie-Tooth disease.
• Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.
• Autoimmunity in visual loss.
• Maintenance Intravenous Fluids in Acutely Ill Patients.
• The prevalence of microcystic macular changes on optical coherence tomography of the macular region in optic nerve atrophy of non-neuritis origin: a prospective study.
• Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis.
• The prognostic value of CSF neurofilaments in multiple sclerosis at 15-year follow-up.
• Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study.
• Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis.
• Optical coherence tomography angiography and retinal microvascular ramification in acute macular neuroretinopathy and paracentral acute middle maculopathy
• Neuroprotection and visual function after optic neuritis
• Retinal glymphatic system: an explanation for transient retinal layer volume changes?
• Case 3-2017: A man with cardiac sarcoidosis and new diplopia and weakness
• Volume rendering of superficial optic disc drusen: A possible new imaging technique using optical coherence tomography angiography,Volumengraphik oberflächlicher Drusenpapillen: Ein mögliches neues Bildgebungsverfahren mittels optischer Kohärenztomographie-Angiographie
• Serum Compounds of Energy Metabolism Impairment Are Related to Disability, Disease Course and Neuroimaging in Multiple Sclerosis
• A rare cause for visual symptoms in multiple sclerosis: posterior internuclear ophthalmoplegia of Lutz, a historical misnomer
• Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: A longitudinal, prospective translational study
• Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis
• Structure-function relationships in the visual system in multiple sclerosis: an MEG and OCT study
• Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study
• Revising the Advised Protocol for Optical coherence tomography Study Terminology and Elements (APOSTEL): from recommendations to formal guidelines
• Retinal Atrophy Measured by Optical Coherence Tomography Predicts Disability Progression in Multiple Sclerosis
• THE EFFECTS OF FAMPRIDINE ON EYE MOVEMENTS IN MULTIPLE SCLEROSIS PATIENTS WITH INTERNUCLEAR OPHTHALMOPLEGIA
• Retinal inner nuclear layer volume: a potential new outcome measure for optic neuritis treatment trials in MS
• Optic neuritis does not mask progression of retinal neurodegeneration in multiple sclerosis
• THE APOSTEL RECOMMENDATIONS FOR REPORTING QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY STUDIES Response
• Updates in OCT segmentation software influence longitudinal assessment of retinal atrophy
• Is there a relationship between saccadic eye movements and cognitive function in multiple sclerosis?
• The relationship of retinal atrophy to visual functioning and vision-related quality of life in patients with multiple sclerosis
• Atrophy of the retinal nerve fiber layer and ganglion cell-inner plexiform layer is associated with cognitive impairment in multiple sclerosis
• Recurrent optic perineuritis after intranasal cocaine abuse
• Bi-directional trans-synaptic degeneration in the visual pathway in multiple sclerosis
• Biomarkers in neurodegenerative disease
• Retinal ganglion cell injury in MS occurs most rapidly early in the course of disease
• Hyperacute steroid therapy in patients with recurrent optic neuritis
• Intrathecal oligoclonal IgG synthesis in multiple sclerosis.
• Should CLIPPERS Be Considered a Prelymphoma State or a New Inflammatory Disease?-Reply.
• The prognostic value of brain extracellular fluid nitric oxide metabolites after traumatic brain injury.
• Fatal B-cell lymphoma following chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids.
• Pain management in neurocritical care.
• Patterns of non-embolic transient monocular visual field loss.
• Loss of retinal nerve fibre layer axons indicates white but not grey matter damage in early multiple sclerosis.
• The utility of cerebrospinal fluid analysis in patients with multiple sclerosis.
• Chronic relapsing inflammatory optic neuropathy: a systematic review of 122 cases reported.
• Cerebrospinal fluid analyses for the diagnosis of subarachnoid haemorrhage and experience from a Swedish study. What method is preferable when diagnosing a subarachnoid haemorrhage?
• Effects of repeated intrathecal triamcinolone-acetonide application on cerebrospinal fluid biomarkers of axonal damage and glial activity in multiple sclerosis patients.
• Cerebrospinal fluid transferrin levels are reduced in patients with early multiple sclerosis.
• Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients.
• Neurodegeneration and Multiple Sclerosis
• Optical Coherence Tomography to Assess Neurodegeneration in Multiple Sclerosis
• Chronic relapsing inflammatory optic neuropathy: a systematic review of 122 cases reported
• Neuro-Ophthalmic Literature Review
• Diagnosis and classification of autoimmune optic neuropathy
• Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids and Fatal B-Cell Lymphoma—Reply
• Neuro-Ophthalmic Literature Review
• Neuro-Ophthalmic Literature Review
• Physiological variation of segmented OCT retinal layer thicknesses is short-lasting
• Current and future potential of retinal optical coherence tomography in multiple sclerosis with and without optic neuritis
• Neurofilaments as a plasma biomarker for ICU-acquired weakness: an observational pilot study
• Distribution of Retinal Layer Atrophy in Patients With Parkinson Disease and Association With Disease Severity and Duration
• The investigation of acute optic neuritis: a review and proposed protocol
• Serum lactate as a novel potential biomarker in multiple sclerosis
• Re: Garcia-Martin et al.: Retinal layer segmentation in patients with multiple sclerosis using spectral domain optical coherence tomography (Ophthalmology 2014;121:573–9)
• Physiological variation of retinal layer thickness is not caused by hydration: A randomised trial
• Visual pathway neurodegeneration winged by mitochondrial dysfunction
• Neurofilament heavy chain as a marker of neuroaxonal pathology and prognosis in acute encephalitis
• Distribution of Retinal Layer Atrophy in Patients With Parkinson Disease and Association With Disease Severity and Duration
• Retinal segmentation to demonstrate hyperplasia in ataxia of Charlevoix-Saguenay: critique on study methodology and results.
• Biomarker time out.
• The clinical spectrum of microcystic macular edema.
• A dam for retrograde axonal degeneration in multiple sclerosis?
• Disease course heterogeneity and OCT in multiple sclerosis.
• Retinal hyperaemia-related blood vessel artifacts are relevant to automated OCT layer segmentation.
• TO OCT OR NOT TO OCT - IS OPTICAL COHERENCE TOMOGRAPHY READY FOR ROUTINE APPLICATION IN MULTIPLE SCLEROSIS?
• The impact of Tween 20 on repeatability of amyloid β and tau measurements in cerebrospinal fluid
• Disorders of plasma sodium
• Pain in optic perineuritis: Author response
• PLASMA NEUROFILAMENT HEAVY CHAIN LEVELS IN CHARCOT-MARIE-TOOTH DISEASE
• Patterns of OCT changes in optic neuritis
• Structural functional relationship in the visual system in multiple sclerosis
• Recurrent laughter-induced syncope
• Microcystic macular oedema in multiple sclerosis
• GLIAL FIBRILLARY ACIDIC PROTEIN: A BIOMARKER FOR GLIAL PATHOLOGY IN HUMAN DISEASE
• META-ANALYSIS OF OCT STUDIES FOR THE ASSESSMENT OF VIGABATRIN-ASSOCIATED RETINAL TOXICITY IN EPILEPSY
• A dam for axonal degeneration in multiple sclerosis
• The clinical spectrum of microcystic macular oedema (MMO)
• Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids and Fatal B-Cell Lymphoma Reponse
• Disease course heterogeneity and optical coherence tomography (OCT) in multiple sclerosis
• Comparison of two retinal nerve fibre layer segmentation algorithms for the Heidelberg Spectralis
• A smouldering fire in the eye: Vuurtje
• Chronic lymphocytic inflammation with Pontine perivascular enhancement responsive to steroids and fatal B-cell lymphoma--reply.
• Biological markers
• Influence of the eye-tracking-based follow-up function in retinal nerve fiber layer thickness using fourier-domain optical coherence tomography.
• A smouldering fire in the eye: vuurtje.
• Embolic and nonembolic transient monocular visual field loss: a clinicopathologic review.
• Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.
• Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis.
• Microcystic macular oedema confirmed, but not specific for multiple sclerosis.
• Comment on "chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model".
• Anti-voltage-gated potassium channel Kv1.4 antibodies in myasthenia gravis.
• Serum GFAP levels in optic neuropathies.
• Glial S100B is elevated in serum across the spectrum of West Nile virus infection.
• Neurofilament heavy chain and heat shock protein 70 as markers of seizure-related brain injury.
• The physiological variation of the retinal nerve fiber layer thickness and macular volume in humans as assessed by spectral domain-optical coherence tomography.
• Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS.
• The OSCAR-IB consensus criteria for retinal OCT quality assessment.
• Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS.
• A simple sign for recognizing off-axis OCT measurement beam placement in the context of multicentre studies.
• Serial soluble neurofilament heavy chain in plasma as a marker of brain injury after cardiac arrest.
• The diagnostic and prognostic value of neurofilament heavy chain levels in immune-mediated optic neuropathies.
• Axonal damage in the making: neurofilament phosphorylation, proton mobility and magnetisation transfer in multiple sclerosis normal appearing white matter.
• Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign.
• Cerebrospinal fluid ferritin level, a sensitive diagnostic test in late-presenting subarachnoid hemorrhage.
• Cognitive, biochemical, and imaging profile of patients suffering from idiopathic normal pressure hydrocephalus.
• What makes a prognostic biomarker in CNS diseases: strategies for targeted biomarker discovery? Part 2: chronic progressive and relapsing disease.
• Neurofilament stoichiometry simulations during neurodegeneration suggest a remarkable self-sufficient and stable in vivo protein structure.
• What makes a prognostic biomarker in CNS diseases: strategies for targeted biomarker discovery? Part 1: acute and monophasic diseases.
• The neurofilament light chain is not stable in vitro.
• Glial but not axonal protein biomarkers as a new supportive diagnostic criteria for Devic neuromyelitis optica? Preliminary results on 188 patients with different neurological diseases.
• Neurofilament heavy chain in CSF correlates with relapses and disability in multiple sclerosis.
• Rostrocaudal dynamics of CSF biomarkers.
• A method to solubilise protein aggregates for immunoassay quantification which overcomes the neurofilament "hook" effect.
• Biomarkers of Disease Progression
• Optic Neuritis: Another Dickensian Diagnosis
• Exceptional preservation of a prehistoric human brain from Heslington, Yorkshire, UK
• Cerebrospinal fluid transferrin levels are reduced in patients with early multiple sclerosis
• Cerebrospinal fluid (CSF) transferrin levels are reduced in patients with early multiple sclerosis
• Serum Biomarkers in the Early Course of Ischemic Stroke: Hyperacute Detection of Neurofilament Heavy Chain
• Multicentre reliability of intra-retinal layer segmentation
• Multicentre inter-rater reliability of retinal layer segmentation using spectral-domain optical coherence tomorgraphy (OCT)
• PLASMA NEUROFILAMENT HEAVY CHAIN LEVELS AS A DISEASE BIOMARKER IN THE SOD1 MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS
• Reply from the authors
• The Epidemiological Profile of Patient Cohort With Isolated Optic Neuritis
• Increasing knowledge of best practices in occupational therapists treating post-stroke unilateral spatial neglect: a pilot study
• Disease-specific cerebrospinal fluid investigations
• NORMAL CSF FERRITIN LEVELS IN MS SUGGEST AGAINST ETIOLOGIC ROLE OF CHRONIC VENOUS INSUFFICIENCY Reply
• Serum neurofilament in patients with relapsing-remitting multiple sclerosis
• Optical coherence tomography - A new monitoring tool for multiple sclerosis?
• A simple OCT sign relevant in the context of multicentre studies: inhomogeneous outer plexiform layer reflectivity
• NORMAL CSF FERRITIN LEVELS IN MS SUGGEST AGAINST ETIOLOGIC ROLE OF CHRONIC VENOUS INSUFFICIENCY Reply
• Atrophy of retinal axons is associated with white but not grey matter damage in early multiple sclerosis - A spectral domain optical coherence tomography-MRI study
• The OSCAR-IB reading centre criteria for retinal OCT studies in multiple sclerosis
• The physiological variation of the retinal nerve fibre layer thickness and macular volume in humans
• In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study.
• Remote ischemic preconditioning protects the brain against injury after hypothermic circulatory arrest.
• International Issues: the EAYNT: ten years of unifying European junior neurologists.
• Matrix metalloproteinases in myasthenia gravis.
• Soluble beta-amyloid precursor protein is related to disease progression in amyotrophic lateral sclerosis.
• The use of serum glial fibrillary acidic protein measurements in the diagnosis of neuromyelitis optica spectrum optic neuritis.
• Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies.
• Blood and CSF Biomarker Dynamics in Multiple Sclerosis: Implications for Data Interpretation.
• Neurodegeneration in MS and NMO: The Eye and the Blood.
• Evidence for acute neurotoxicity after chemotherapy.
• Batch prepared protein standards for cerebrospinal fluid (CSF) biomarkers for neurodegeneration.
• Normal CSF ferritin levels in MS suggest against etiologic role of chronic venous insufficiency.
• Urinary neopterin and nitric oxide metabolites as markers of interferon beta-1a activity in primary progressive multiple sclerosis.
• Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis.
• Anti-Heat Shock Protein 70 antibody levels are increased in myasthenia gravis and Guillain-Barre syndrome.
• [Cerebrospinal fluid-based diagnostics of CT-negative subarachnoid haemorrhage].
• Differential pattern of brain-specific CSF proteins tau and amyloid-β in Parkinsonian syndromes.
• An unbiased, staged, multicentre, validation strategy for Alzheimer's disease CSF tau levels.
• Cerebrospinal fluid ATP metabolites in multiple sclerosis.
• Recurrent ptosis due to myopathy of the levator palpebrae superioris.
• Short commentary on 'a consensus protocol for the standardization of cerebrospinal fluid collection and biobanking'.
• Neurology training around the world: asking the trainees.
• Neuronal and glial cerebrospinal fluid protein biomarkers are elevated after West Nile virus infection.
• Neurofilament ELISA validation.
• Neuromyelitis optica-IgG (aquaporin-4) autoantibodies in immune mediated optic neuritis.
• The longitudinal profile of bilirubin and ferritin in the cerebrospinal fluid following a subarachnoid hemorrhage: diagnostic implications.
• A novel biomarker for retinal degeneration: vitreous body neurofilament proteins.
• A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking.
• Erratum to: Rostrocaudal Dynamics of CSF Biomarkers.
• Neurofilament ELISA validation
• A consensus protocol for the standardisation of cerebrospinal fluid collection and biobanking
• Neuronal and glial cerebrospinal fluid protein biomarkers are elevated after West Nile Virus Infection
• Axonal Damage in the Making: Neurofilament Phosphorylation and Magnetization Transfer in Multiple Sclerosis Non-Lesional White Matter
• In multiple sclerosis' protein phosphorylation competes with the free proton binding capacity in post-mortem brain tissue
• NEUROFILAMENT HEAVY CHAIN AND HSP-70 AS MARKERS OF SEIZURE-RELATED BRAIN INJURY
• Serum GFAP levels distinguish NMO from other optic neuropathies
• Novel CSF Biomarkers of Disease Progression of Amyotrophic Lateral Sclerosis
• Plasma neurofilament levels as a biomarker of disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis
• High CSF-neurofilament heavy chain levels in neuromyelitis optica
• Repeated intrathecal triamcinolone acetonide application in multiple sclerosis patients: clinical aspects and effects on cerebrospinal fluid marker of astrocytic activation
• Increase of uric acid and purine compounds in serum of multiple sclerosis patients
• Effects of Repeated Intrathecal Triamcinolone Acetonid Application on Cerebrospinal Fluid Biomarkers of Axonal Damage and Glial Activity in Multiple Sclerosis Patients
• Assessing visual fields for driving in patients with paracentral scotomata
• Intravenous immunoglobulin treatment reduces cerebrospinal fluid and serum nitric oxide metabolite levels in chronic widespread pain syndromes
• Serum neurofilament levels suggest axonal damage is more extensive in neuromyelitis optica than in neuromyelitis optica or multiple sclerosis optic neuritis
• H2O coma
• The value of the serum neurofilament protein heavy chain as a biomarker for peri-operative brain injury after carotid endarterectomy.
• The longitudinal profile of CSF markers during external lumbar drainage.
• Cerebrospinal fluid biomarkers in multiple sclerosis.
• Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients.
• CSF protein biomarkers for proximal axonal damage improve prognostic accuracy in the acute phase of Guillain-Barre syndrome.
• Improving the recovery of S100B protein in cerebral microdialysis: implications for multimodal monitoring in neurocritical care.
• EFNS guidelines on disease-specific CSF investigations.
• Glial fibrillary acidic protein in Guillain-Barre syndrome: Methodological issues.
• A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease.
• Longitudinal one-year study of levels and stoichiometry of neurofilament heavy and light chain concentrations in CSF in patients with multiple system atrophy.
• Cerebrospinal fluid biomarkers in Guillain-Barre syndrome--where do we stand?
• Phosphorylation and compactness of neurofilaments in multiple sclerosis: indicators of axonal pathology.
• Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study.
• Cerebrospinal fluid brain specific proteins in relation to nitric oxide metabolites during relapse of multiple sclerosis.
• High CSF neurofilament heavy chain levels in neuromyelitis optica.
• Comparison of two ELISA methods for measuring levels of the phosphorylated neurofilament heavy chain.
• CSF neurofilaments in frontotemporal dementia compared with early onset Alzheimer's disease and controls.
• Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis.
• Marathon related death due to brainstem herniation in rehydration-related hyponatraemia: a case report.
• A systematic review and meta-analysis of CSF neurofilament protein levels as biomarkers in dementia.
• Neuronal Cell Death and Axonal Degeneration: Neurofilaments as Biomarkers
• Synchronised Paroxysmal Ocular Tilt Reaction and Limb Dystonia
• CSF protein biomarkers for proximal axonal damage improve prognostic accuracy in the acute phase of Guillain-Barré syndrome
• EFNS guidelines on disease-specific CSF investigations.
• Glial fibrillary acidic protein in Guillain-Barré syndrome: Methodological issues
• Neuronal cell death and axonal degeneration: Neurofilaments as biomarkers
• The historical origin of the Pulfrich effect: a serendipitous astronomic observation at the border of the Milky Way
• Synchronised paroxysmal ocular tilt reaction and limb dystonia
• Glial and axonal body fluid biomarkers are related to infarct volume, severity, and outcome
• Glial and axonal body fluid biomarkers are related to infarct volume, severity, and outcome.
• Marathon related death due to brainstem herniation in rehydration-related hyponatraemia: a case report
• High CSF-neurofilament heavy chain levels in neuromyelitis optica
• EFNS guidelines on disease-specific CSF investigations
• EVALUATION OF NEUROFILAMENT PROTEIN HEAVY CHAINS IN SERUM AS BIOMARKER FOR PERI-OPERATIVE BRAIN AFTER CAROTID ENDARTERECTOMY
• Biomarkers in MSA and PSP: Cerebrospinal fluid concentrations of axonal markers and beta-Amyloid
• Aquaporin-4 autoantibodies define autoimmune optic neuritis
• NMO-IgG serology in chronic relapsing inflammatory optic neuropathy
• Chronic relapsing inflammatory optic neuropathy: An extension of the neuromyelitis optica spectrum disorder
• Glia response markers in relation to nitric oxide metabolites in the CSF of relapsing multiple sclerosis patients
• Acute treatment related neurotoxicity in secondary progressive multiple sclerosis
• Highly sensitive electrochemiluminescence-based immunoassay to determine the neurofilament heavy chain as a marker of axonal damage in multiple sclerosis
• Axonal and glial biomarkers in atypical parkinsonian syndromes: Implications for the laboratory supported differential diagnosis
• Acetazolamide responsive paroxysmal ocular tilt reaction synchronised with focal limb dystonia: Discussion of the likely anatomical substrate
• High CSF-neurofilament heavy chain levels in neuromyelitis optica: distinction from multiple sclerosis
• Accelerated axonal degeneration after bonemarrow transplantation for aggressive multiple sclerosis?
• Axonal damage markers in cerebrospinal fluid of patients with clinically isolated syndrome and early multiple sclerosis
• The value of lumbar cerebrospinal fluid levels of neurofilaments in the differential diagnosis of patients with dementia
• Stoichiometry of the CSF neurofilament heavy and light chains
• The impact of imported MRSA for a hospital
• Stroke volume, clinical severity and functional outcome in stroke are related to CSF levels of glial and axonal biomarkers
• Influence of repeat intrathecal triamcinolone acetonid application on cerebrospinal fluid and serum biomarkers in multiple sclerosis patients
• 4-Dihydromethyltrisporate dehydrogenase, an enzyme of the sex hormone pathway in Mucor mucedo, is constitutively transcribed but its activity is differently regulated in (+) and (−) mating types
• Neurofilament heavy-chain NfH(SMI35) in cerebrospinal fluid supports the differential diagnosis of Parkinsonian syndromes.
• Increased urinary excretion of nitric oxide metabolites in longitudinally monitored migraine patients.
• Free phenytoin concentration measurement in brain extracellular fluid: a pilot study.
• CSF neurofilament levels: a potential prognostic marker in Guillain-Barre syndrome.
• Early identification of secondary brain damage in subarachnoid hemorrhage: a role for glial fibrillary acidic protein.
• Axonal damage and outcome in subarachnoid haemorrhage.
• Axonal damage markers in the cerebrospinal fluid of patients with clinically isolated syndrome improve predicting conversion to definite multiple sclerosis.
• Measurement of high affinity antibodies on antigen-immunoblots.
• Axonal damage markers in cerebrospinal fluid are increased in ALS.
• High intracranial pressure, brain herniation and death in cerebral venous thrombosis.
• Extracellular N-acetylaspartate depletion in traumatic brain injury.
• Educational approach on stroke training in Europe.
• The neurofilament heavy chain (NfH) in the cerebrospinal fluid diagnosis of Alzheimer's disease.
• Amniotic fluid brain-specific proteins are biomarkers for spinal cord injury in experimental myelomeningocele.
• Optic flow induced nystagmus.
• Extracellular fluid S100B in the injured brain: a future surrogate marker of acute brain injury?
• No evidence for MSRV viraemia and glial cell death in acute optic neuritis.
• Why human color vision cannot reliably detect cerebrospinal fluid xanthochromia.
• Decreased CSF hypocretin-1 (orexin-A) after acute haemorrhagic brain injury.
• The Bryan cervical disc prosthesis as an alternative to arthrodesis in the treatment of cervical spondylosis: 46 consecutive cases.
• Axonal pathology in subarachnoid and intracerebral hemorrhage.
• Axonal damage accumulates in the progressive phase of multiple sclerosis: three year follow up study.
• Central and paracentral visual field defects and driving abilities.
• Brain Extracellular Fluid Nitrite/Nitrate Levels after Traumatic Brain Injury are Related to Survival
• Axonal damage markers in the cerebrospinal fluid of patients with clinically isolated syndrome improve predicting conversion to definite multiple sclerosis.
• Spectrophotometry for cerebrospinal fluid pigment analysis: a review
• Neurofilament heavy chain NfH(SMI35) in cerebrospinal fluid supports the differential diagnosis of Parkinsonian syndromes
• The new global multiple sclerosis severity score (MSSS) correlates with axonal but not glial biomarkers
• The new global multiple sclerosis severity score (MSSS) correlates with axonal but not glial biomarkers.
• Axonal damage markers in the cerebrospinal fluid of patients with clinically isolated syndrome improve predicting conversion to definite multiple sclerosis.
• Cross-validation of two ELISA methods for measuring levels of the phosphorylated neurofilament heavy chain
• Intra-arterial papaverine used to treat cerebral vasospasm reduces brain oxygen
• The new global multiple sclerosis severity score (MSSS) correlates with axonal but not glial biomarkers.
• Raised urinary neopterin excretion is associated with a better clinical outcome in PP-MS patients treated with interferon beta-1a
• Differences in TRADD expression indicated by array analysis discriminates between NIS disease subtypes
• Different TRADD expression discriminates between multiple sclerosis disease subtypes
• Kynurenic acid concentrations in relation to the expression of ferritin and S-100B in the CSF of relapsing multiple sclerosis patients
• Impaired energy metabolism and increased lipid peroxidation in multiple sclerosis
• Expression of ferritin and S-100B in relation to nitric oxide metabolites in the cerebrospinal fluid of relapsing multiple sclerosis patients
• Transient monocular blindness: The controversial role of the ophthalmic artery: Response to Rutgers et al. in J Neurol (2003) 250:501-502 [1] (multiple letters)
• Cerebrospinal fluid apolipoprotein E concentration decreases after traumatic brain injury
• Alterations in Cerebrospinal Fluid Apolipoprotein E and Amyloid β-Protein after Traumatic Brain Injury
• Localization of endothelin receptors in bleomycin-induced pulmonary fibrosis in the rat
• Brain extracellular fluid biomarkers predict intracranial hypertension in traumatic brain injury
• Brain extracellular fluid S-100B levels correlate with mortality in acute brain injury
• Prediction of secondary brain injury during neurocritical care: The role of cerebral microdialysis
• Axonal damage markers in CSF of patients with amyotrophic lateral sclerosis
• Axonal markers (neurofilaments) predict outcome in Guillain-Barre syndrome
• Monitoring secondary brain injury in subarachnoid haemorrhage: a role for GFAP
• No evidence for MSRV viraemia and glial cell death in acute optic neuritis.
• CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis
• Marathon related death
• Increased phosphorylation of axonal neurofilaments in multiple sclerosis
• From basic science to clinical practise: Xanthochromia in neurocritical care
• Axonal damage markers in CSF of patients with clinically isolated syndrome and early MS
• Atypical transient monocular blindness
• CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis.
• Axonal degeneration and inflammation in acute optic neuritis.
• Transient monocular blindness: the controversial role of the ophthalmic artery--response to Rutgers et al. in J Neurol (2003) 250:501-502.
• Treatment response in relation to inflammatory and axonal surrogate marker in multiple sclerosis.
• An ELISA for glial fibrillary acidic protein.
• Cerebrospinal fluid nitrite/nitrate correlated with oxyhemoglobin and outcome in patients with subarachnoid hemorrhage.
• Serum S100B in primary progressive multiple sclerosis patients treated with interferon-beta-1a.
• Cannabinoids inhibit neurodegeneration in models of multiple sclerosis.
• Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage.
• Alterations in cerebrospinal fluid apolipoprotein E and amyloid beta-protein after traumatic brain injury.
• Cerebrospinal fluid (CSF) and serum S100B: release and wash-out pattern.
• Impaired fibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors.
• A specific ELISA for measuring neurofilament heavy chain phosphoforms.
• Quantification of neurodegeneration by measurement of brain-specific proteins.
• Cerebrospinal fluid apolipoprotein E concentration decreases after traumatic brain injury.
• Decreased cerebrospinal fluid apolipoprotein E after subarachnoid hemorrhage: correlation with injury severity and clinical outcome.
• Multiple sclerosis: Neurofilament light chain antibodies are correlated to cerebral atrophy.
• Cerebrospinal fluid S100B correlates with brain atrophy in Alzheimer's disease.
• The Bryan cervical disc prosthesis as an alternative to arthrodesis in the treatment of cervical spondylosis: 46 CONSECUTIVE CASES
• The pro and the active form of matrix metalloproteinase-9 is increased in serum of patients with amyotrophic lateral sclerosis
• Visual assessment for xanthochromia needs no revisitation
• No evidence for MSRV viraemia and glial cell death in acute optic neuritis.
• Prediction of secondary brain injury during neurocritical care: The role of cerebral microdialysis. In: Microdialysis monitoring tissue chemistry in intensive care medicine
• CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis
• CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis
• Cerebrospinal fluid (CSF) and serum S100B: release and wash-out pattern
• The Bryan cervical disc prosthesis as an alternative to arthrodesis in the treatment of cervical spondylosis
• Gene expression analysis indicates distinct immune pattern in relapsing remitting (RR) and primary progressive (PP) MS disease type
• Decreased CSF hypocretin-1 (orexin-A) in patients after acute haemorrhagic brain stroke
• Axonal pathology in subarachnoid and intracerebral haemorrhage
• Raised serum nitric oxide metabolites are related to disease activity in patients with multiple sclerosis: 1-year follow-up study
• The Global Multiple Sclerosis Severity Score (MSSS) correlates with axonal but not glial biomarkers
• No association of apoE concentration in CSF with clinical arid MR1 characteristics in MS
• Repetitive cerebral bleeding in an adult with Klippel-Trenaunay syndrome
• Role of serum S100B as an early predictor of high intracranial pressure and mortality in brain injury: A pilot study